Drug discovery • Biodefense • One TRL9 platformDrug Discovery: We don’t change the target. We find the right cell.
Most important drug targets never reach the surface of ordinary lab cells. Instead of altering the protein, Chromovert® uses color-coded molecular beacons and high-speed sorting to find the rare cells that make the native protein, then keeps the ones that work and stay stable. Two minute video, no biology degree required.
Applied to numerous ion channel and GPCR targets • Targets out of reach by traditional methods • Hits confirmed in humans without re-optimization
Biodefense: What if adversaries use AI to create new nerve agents?
Chromovert® builds living cells that carry human targets in their native form, exactly as they exist in the body. The missing link for rapid countermeasure discovery, and for CNS drug discovery.
BiodefenseRapid countermeasure discovery. Build a living cell for every target a new agent could strike, then find the approved drugs that oppose it. The briefing above makes the case. A candidate countermeasure in days, not years.
Drug discoveryChromovert® is a target-agnostic platform. It builds native cells for GPCRs, ion channels and other target classes, including the brain receptors behind neurological and psychiatric disease. Cells with native targets give data that reflects real human biology and is strong enough to train AI models.
The platform
Validated. TRL9. Ready.
Chromovert® was invented at Rockefeller University and has since been validated through more than $150 million in research, development, and collaboration programs. It is a TRL9 platform, proven in real-world use, now applied to biodefense and drug discovery.
Founder and CEO
Kambiz Shekdar, PhD
Inventor of Chromovert® technology as a graduate fellow in the lab of Nobel laureate Günter Blobel. CEO of Secondcell Bio.
Connecting the biotech community
“Another Boston Biotech Event! - First Mondays”
A monthly mixer on the first Monday of each month in Cambridge, with quarterly panels.
Biotech CEOs on the BIZ with Dr. Kambiz!
In-person conversations with biotech CEOs about the science, the bets and the people behind them.
Explainer videos on hot topics
Learn about organoids, iPS cells, cell therapy, Parkinson’s and other fields where Chromovert® can help. Biotech degree not required!
Let’s work together
Whether you're a pharma partner, an investor, or working on a hard-to-express target, we'd like to hear from you.